EDUCATION / CURRICULUM / PATHWAY 05
PATHWAY 05 / GENEXOME LEARNING LABORATORY

Gene Editing & Medicine

What changes when we can investigate or modify biological information?

Variantsgene functioneditingethics
QUESTIONS THAT OPEN DOORS

Begin with curiosity.

INVESTIGATION 01

Can a change in DNA always correct disease?

Observe a phenomenon, make a prediction, investigate a simplified model, evaluate evidence and explain the result.

INVESTIGATION 02

What must be evaluated before a treatment?

Observe a phenomenon, make a prediction, investigate a simplified model, evaluate evidence and explain the result.

WHAT LEARNERS CAN PRACTISE

Understanding becomes something you can do.

LEARNING INTENTION / 01

Distinguish a pathogenic variant from an ordinary difference

Suggested learning goal; not a measured or accredited outcome.

LEARNING INTENTION / 02

Explain CRISPR conceptually and its limitations

Suggested learning goal; not a measured or accredited outcome.

LEARNING INTENTION / 03

Discuss safety, access and evidence in therapeutic research

Suggested learning goal; not a measured or accredited outcome.

EXPAND THE INVESTIGATION

A classroom-ready inquiry structure.

01 / Observe

Start with: “Can a change in DNA always correct disease?” Describe what is known, what is observed and what remains unclear.

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02 / Predict

Invite learners to offer at least two possible explanations and predict how a change in conditions might affect the outcome.

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03 / Experiment

Use an age-appropriate visual or simplified model. Change one variable at a time and document the result; do not perform clinical or biological interventions.

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04 / Verify

Compare observations with the original prediction. Identify model assumptions, alternative explanations and missing empirical evidence.

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05 / Explain

Ask learners to communicate a claim, its supporting observations, its limitations and the next question they would investigate.

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